DEVOMSuiteR

• DEVCOMSuiteR Pipeline: Cell–Cell Communication and Pathway Analysis
• 1. Data and Environment
• 2. Inference of Cell–Cell Communication Networks
  • 2.1 Running compute_cc_networks_devcom()
• 3. Communication Heatmap
  • 3.1 Plotting global communication strength
• 1. GO Annotation and Pathway Activity Analysis
  • 4.1 GO block construction and integration
  • 4.2 Merging GO blocks across LR / RTF / TFT
  • 4.3 GO pathway activity for a single file
  • 4.4 Batch GO pathway activity over a directory
• 5. KEGG Annotation and Pathway Activity
  • 5.1 KEGG annotation for LR / RTF / TFT blocks
  • 5.2 Integrating KEGG annotations across LR / RTF / TFT
  • 5.3 KEGG pathway activity scores
  • 5.4 Selecting developmental KEGG pathways
• 6. Active vs Inhibitory Signaling Classification
  • 6.1 Computing active/inhibitory signaling scores
  • 6.2 Global communication circos plot
• 7. Differential Communication Between Conditions
  • 7.1 Running differential communication analysis